Syllabus

Curriculum Outline:

Module 1 - Background

1.0 Introduction

Module 2 - Diabetes

2.0 Introduction
2.1 Diabetes Epidemiology
2.2 Pre-diabetes
2.3 Metabolic Syndrome
2.4 Diabetes Risk Factors
2.5 Diabetes Complications
2.6 Summary

Module 3 - Diabetic Eye Disease

3.0 Introduction
3.1 Epidemiology
3.2 DR/DME Risk Factors
3.3 Summary

Module 4 - Role of Blood Vessels

4.0 Introduction
4.1 Healthy Blood Vessels
4.2 Stimulating Growth
4.3 VEGF and Vessel Permeability
4.4 Role of Blood Vessels in Ocular Disease
4.5 Summary

Module 5 - The Retina

5.0 Introduction
5.1 The Human Eye and Retinal Structure
5.2 Retinal Vasculature
5.3 Retinal Cell Types that Produce VEGF
5.4 Summary

Module 6 - DR/DME Etiology

6.0 Introduction
6.1 Metabolic Pathway to DME
6.2 Hyperglycemia
6.3 PKC
6.4 Oxidative Stress
6.5 AGEs
6.6 Polyol Pathway
6.7 Hexosamine Pathway
6.8 R-A System
6.9 Inflammation
6.10 Retinal Vessel Changes (include hypertension)
6.11 Retinal Changes and Edema
6.12 Summary

Module 7 - DR/DME Diagnosis

7.0 Introduction
7.1 Color Fundus Photography
7.2 Fluorescein Angiography
7.3 Ocular Coherence Tomography
7.4 Other types of OCT
7.5 The future of Detection
7.6 Symptoms and Onset
7.7 Summary

Module 8 - DR/DME Classifications

8.0 Introduction
8.1 DR Severity Scale
8.2 DME Classifications
8.3 Proposed Phenotypes of DR/DME
8.4 Summary

Module 9 - Treatments

9.0 Introduction
9.1 Anti-VEGF Treatments
9.2 Biology and pharmacology of anti-VEGF therapies
9.3 Avastin
9.4 Lucentis
9.5 Eylea
9.6 Side Effects
9.7 Laser Therapy
9.8 Corticosteroids
9.9 Vitrectomy
9.10 Future Technology
9.11 Assessment of treatment value
9.12 Summary

Module 10 - Clinical Studies & Treatment Data

10.0 Introduction
10.1 READ-2
10.2 RESOLVE
10.3 FAME
10.4 BOLT
10.5 DRCR.net Protocol I
10.6 CHAMPLAIN
10.7 RIDE/RISE
10.8 PLACID
10.9 MEAD
10.10 RESTORE
10.11 VIVID/VISTA
10.12 DRCR.net Protocol T
10.13 Ongoing Studies
10.14 Summary: Putting It All Together