9.8 Corticosteroids


Corticosteroids have emerged as an alternative therapy for persistent DME or DME refractory to conventional laser photocoagulation and other treatments. These agents have characteristics that result in the inhibition of vascular endothelial growth factor (VEGF) and possess anti-inflammatory properties.

Quiz Module 9.8

1. What are two important mechanisms for corticosteroid actions applicable to the treatment of DME?

2. Which of the following corticosteroids are available as intravitreal inserts for the treatment of DME?

3. One of the primary anti-inflammatory mechanisms of corticosteroids is their inhibition of the arachidonic acid cascade.

4. What are some obvious advantages of administering corticosteroids via intravitreal inserts compared with intravitreal injections?