9.8 Corticosteroids

Quiz Module 9.8

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1. What are two important mechanisms for corticosteroid actions applicable to the treatment of DME?

a. Inhibition of vascular endothelial growth factor (VEGF), anti-inflammatory properties

b. Anti-inflammatory properties, excitation of vascular endothelial growth factor (VEGF)

c. Antihistaminic properties, inhibition of vascular endothelial growth factor (VEGF)

d. Inhibition of endothelial growth factor (EGF) binding, competitive binding of vascular endothelial growth factor receptor (VEGFR)

2. Which of the following corticosteroids are available as intravitreal inserts for the treatment of DME?

a. Fluocinolone acetonide

b. Dexamethasone

c. Triamicinolone

d. A and B

3. One of the primary anti-inflammatory mechanisms of corticosteroids is their inhibition of the arachidonic acid cascade.

a. True

b. False

4. What are some obvious advantages of administering corticosteroids via intravitreal inserts compared with intravitreal injections?

a. Reduced need for injections and their associated risks

b. Prolonged dosing of the therapeutic agent

c. Less frequent dosing

d. All of the above